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J Am Chem Soc. 2006 Apr 19;128(15):4950-1.

Communicating chemical congregation: a molecular AND logic gate with three chemical inputs as a "lab-on-a-molecule" prototype.

Author information

  • 1School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG, Northern Ireland. d.magri@qub.ac.uk

Abstract

We demonstrate the first three-input molecular AND logic gate based on three chemical inputs as a direct way of detecting congregations of chemical species. The AND gate operates in water and responds to Na+, H+, and Zn2+ inputs with an enhanced fluorescence signal when pre-set concentration thresholds are exceeded. Future "lab-on-a-molecule" devices could have application in medicine for rapid disease screening.

PMID:
16608318
DOI:
10.1021/ja058295+
[PubMed]
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