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Nat Rev Mol Cell Biol. 2006 Apr;7(4):243-52.

Organelles on the move: insights from yeast vacuole inheritance.

Author information

1
Department of Cell and Developmental Biology and Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA. lweisman@umich.edu

Abstract

Organelle inheritance is one of several processes that occur during cell division. Recent studies on yeast vacuole inheritance have indicated rules that probably apply to most organelle-inheritance pathways. They have uncovered a molecular mechanism for membrane-cargo transport that is partially conserved from yeast to humans. They have also shown that the transport complex, which is composed of a molecular motor and its receptor, regulates the destination and timing of vacuole movement and might coordinate organelle movement with several other organelle functions.

PMID:
16607287
DOI:
10.1038/nrm1892
[Indexed for MEDLINE]

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