Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Surg Pathol. 1991 Dec;15(12):1157-64.

Microvillous inclusion disease. The importance of electron microscopy for diagnosis.

Author information

1
Department of Pathology, Stanford University Medical Center, California.

Abstract

We report two cases of microvillous inclusion disease (MID) occurring in a set of siblings. Although it is a rare disorder, MID appears to be a common cause of familial intractable secretory diarrhea. Diagnosis rests on the ultrastructural finding of intracytoplasmic inclusions that are lined by intact microvilli. These inclusions are present in the absorptive surface epithelial cells of the small and large intestine and are associated with poorly developed surface brush border microvilli. The prognosis of MID is poor and curative therapy is not currently available. Because MID appears to be a hereditary disorder, genetic counseling of affected families is essential.

Comment in

PMID:
1660676
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center