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Chem Pharm Bull (Tokyo). 2006 Apr;54(4):485-92.

Syntheses of model compounds related to an antigenic epitope in pectic polysaccharides from Bupleurum falcatum L. (II).

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1
Kyoritsu University of Pharmacy, Tokyo, Japan.

Abstract

Stereocontrolled syntheses of model compounds related to a major antigenic epitope against antibupleurum 2IIc/PG-1-IgG from antiulcer pectic polysaccharide are described. A trisaccharide derivative (13) was prepared as a precursor and a novel and simple approach for the rational design of a glycocluster and glycodendrimer was developed, through the syntheses of the fluorescence-labeled glycocluster (2) and glycodendrimer (3).

PMID:
16595950
[Indexed for MEDLINE]
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