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Urologe A. 2006 Jun;45(6):728-33.

[Psychosocial aspects of interstitial cystitis. Do biographical factors have a relevant impact on the disease course?].

[Article in German]

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Urologische Abteilung, Bundeswehrkrankenhaus, Scharnhorststrasse 13, 10115, Berlin.



The present study explores the influence of psychosocial adversities on the etiology and progress of interstitial cystitis (IC).


A systematic survey of the childhood risk factors was carried out using a specially developed, structured interview for pain patients (MSBA-Mainzer Strukturierte Biographische Anamnese) and additionally the Brief Symptom Inventory (BSI). Essentially a descriptive evaluation was performed. Thirty IC patients who fulfilled the current diagnostic criteria participated in the study.


The investigation showed higher values for relevant childhood adversities in IC patients. A poor emotional relationship with both parents, chronic diseases of the parents, and physical maltreatment were frequently reported. In the cumulative adverse childhood experience score IC patients showed higher levels than published data of healthy control groups. The contemporary social history did not show relevant psychosocial adversities. The quality of life is extremely reduced because of IC symptoms. The BSI showed high levels especially in the dimensions somatization, anxiety, and phobic anxiety.


The results of this study argue for a participatory role of psychosomatic factors in the assumed multifactorial etiology of interstitial cystitis.

[Indexed for MEDLINE]

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