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Crit Care Resusc. 2002 Jun;4(2):112-5.

Hepatic and renal failure associated with amiodarone infusion in a patient with hereditary fructose intolerance.

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Intensive Care Unit, Waikato Hospital, Hamilton, New Zealand.


Hereditary fructose intolerance is a rare inherited metabolic disorder. Although fructose intolerance usually presents in the paediatric age group, individuals can survive into adulthood by self.manipulation of diet. Hospitalisation can become a high.risk environment for these individuals because of loss of control of their strict dietary constraints and the added danger of administration of medications containing fructose, sucrose and sorbitol. We report a case of hereditary fructose intolerance in an adult presenting with hepatic and renal failure associated with an amiodarone infusion and explore the possibility of polysorbate 80 as a cause of this patient's hepatic and renal failure.


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