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Antimicrob Agents Chemother. 2006 Apr;50(4):1581-5.

Induction of daptomycin heterogeneous susceptibility in Staphylococcus aureus by exposure to vancomycin.

Author information

1
Division of Infectious Diseases, New York Medical College, Munger Pavilion, Room 245, Valhalla, NY 10595, USA. george_sakoulas@nymc.edu

Abstract

We studied vancomycin and daptomycin susceptibility in methicillin-resistant Staphylococcus aureus from patients exposed to vancomycin, glycopeptide-intermediate S. aureus, and S. aureus passaged in vancomycin-containing medium. A correlation between vancomycin and daptomycin heteroresistance was noted in some strains, suggesting that exposure of S. aureus to vancomycin may affect susceptibility to daptomycin.

PMID:
16569891
PMCID:
PMC1426932
DOI:
10.1128/AAC.50.4.1581-1585.2006
[Indexed for MEDLINE]
Free PMC Article
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