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J Phys Chem B. 2006 Mar 30;110(12):5854-64.

Chirped coherent anti-stokes Raman scattering for high spectral resolution spectroscopy and chemically selective imaging.

Author information

1
Department of Chemistry, University of California, Berkeley, California 94720, USA.

Abstract

We describe a simple multiplex vibrational spectroscopic imaging technique based on employing chirped femtosecond pulses in a coherent anti-Stokes Raman scattering (CARS) scheme. Overlap of a femtosecond Stokes pulse with chirped pump/probe pulses introduces a temporal gate that defines the spectral resolution of the technique, allowing single-shot acquisition of high spectral resolution CARS spectra over a several hundred wavenumber bandwidth. Simulated chirped (c-) CARS spectra match the experimental results, quantifying the dependence of the high spectral resolution on the properties of the chirped pulse. c-CARS spectromicroscopy offers promise as a simple and generally applicable high spatial resolution, chemically specific imaging technique for studying complex biological and materials samples.

PMID:
16553391
DOI:
10.1021/jp052416a

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