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Dig Liver Dis. 2006 Aug;38(8):609-11. Epub 2006 Mar 23.

Colon and gastric metastases from a primary signet-ring cell carcinoma of the urinary bladder.

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  • 1Department of Clinical and Experimental Medicine, Clinic of Gastroenterology and Hepatology, University of Perugia, Perugia, Italy.


Signet-ring cell carcinoma is a relatively rare neoplasm that rarely occurs in the urinary bladder. We report a case of a 60-year-old man who presented with gross haematuria. Cystoscopy revealed a white sessile tumour of the anterior bladder wall. The histological diagnosis showed a primary signet-ring cell carcinoma of the bladder (T3bN0M0). Eighteen months after radical cystectomy, the patient developed colon and stomach metastases. This case represents the first description of a primary signet-ring cell carcinoma of the urinary bladder with gastrointestinal metastases.

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