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J Am Geriatr Soc. 2006 Mar;54(3):438-43.

The effects of 6 months of increased water intake on blood sodium, glomerular filtration rate, blood pressure, and quality of life in elderly (aged 55-75) men.

Author information

1
Department of General Practice, Research Institute Caphri, Maastricht University, Maastricht, the Netherlands. mspigt@hag.unimaas.nl

Abstract

OBJECTIVES:

To study whether there are any negative or positive effects of 6 months of increased fluid intake in reasonably healthy elderly men.

DESIGN:

Randomized trial.

SETTING:

Community-based.

PARTICIPANTS:

One hundred forty-one healthy participants aged 55 to 75.

INTERVENTION:

One group was given the advice to increase their daily fluid intake by 1.5 L of water; the other group was given placebo medication (8 mL inactive syrup per day).

MEASUREMENTS:

At 6 months blood sodium, glomerular filtration rate (GFR), blood pressure, and quality of life (QOL) were measured. The changes in water turnover were measured using deuterium.

RESULTS:

Most subjects did not manage to increase their fluid intake by 1.5 L. The average increase in the intervention group was approximately 1 L. Twenty-four-hour water turnover in the water group was 359 mL (95% confidence interval=171-548) higher than that of the control group at 6-month follow-up. Blood pressure, sodium level, GFR, and QOL did not change significantly in either group during the intervention period. In addition, the cases reporting a worsening on the effect measures were equally distributed over the two study groups.

CONCLUSION:

The advice to increase fluid intake by 1.5 L had no negative effects in reasonably healthy men aged 55 to 75.

[Indexed for MEDLINE]

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