Format

Send to

Choose Destination
J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2006 Aug;192(8):777-84. Epub 2006 Mar 21.

How silent is the brain: is there a "dark matter" problem in neuroscience?

Author information

1
Faculty of Biomedical Engineering, Technion-Israel Institute of Technology, Technion, Haifa 32000, Israel.

Abstract

Evidence from a variety of recording methods suggests that many areas of the brain are far more sparsely active than commonly thought. Here, we review experimental findings pointing to the existence of neurons which fire action potentials rarely or only to very specific stimuli. Because such neurons would be difficult to detect with the most common method of monitoring neural activity in vivo-extracellular electrode recording-they could be referred to as "dark neurons," in analogy to the astrophysical observation that much of the matter in the universe is undetectable, or dark. In addition to discussing the evidence for largely silent neurons, we review technical advances that will ultimately answer the question: how silent is the brain?

PMID:
16550391
DOI:
10.1007/s00359-006-0117-6
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center