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Scand J Gastroenterol. 1991 Jul;26(7):747-50.

Ispaghula husk may relieve gastrointestinal symptoms in ulcerative colitis in remission.

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1
Dept. of Internal Medicine, Central Hospital, Norrköping, Sweden.

Abstract

The efficiency of ispaghula husk in relieving gastrointestinal symptoms in patients with ulcerative colitis in remission was studied in a placebo-controlled trial running for 4 months. Twenty-nine patients (81%) completed the trial; four withdrew after colitis relapse (three while receiving placebo). Grading of symptoms judged ispaghula to be consistently superior to placebo (p less than 0.001) and associated with a significantly higher rate of improvement (69%) than placebo (24%) (p less than 0.001). The results show that ispaghula can be helpful in the management of gastrointestinal symptoms in quiescent ulcerative colitis.

PMID:
1654592
DOI:
10.3109/00365529108998594
[Indexed for MEDLINE]

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