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Neuroradiology. 2006 Apr;48(4):264-8. Epub 2006 Mar 15.

Single-center experience with TruFill platinum coils for the embolization of cerebral aneurysms.

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Institute of Neuroradiology, JWGU, Frankfurt am Main, Germany.


Endovascular coiling has become a powerful alternative to neurosurgical clipping of cerebral aneurysms. Apart from the Guglielmi Detachable Coil (GDC) (Boston Scientific, Galway, Ireland), there is limited published data about the newer generation of detachable platinum coils, e.g., TruFill (Cordis, Johnson and Johnson, Miami, Fl.). We report our initial clinical experience with the embolization of aneurysms by TruFill coils. Included in this retrospective study were 26 patients (age 55.4+/-14.5 years; 9 male, 17 female) with 28 aneurysms, 21 ruptured and 7 unruptured. All patients were treated exclusively by embolization with TruFill platinum coils. Immediate angiographic and 6-month angiographic follow-up results were documented. Acute clinical outcome was recorded. Of the 28 aneurysms, 16 (57%) were completely occluded by TruFill embolization, 11 (39%) were incompletely occluded with residual necks, and 1 (4%) was partially occluded as residual aneurysm. There were no aneurysmal ruptures during the procedures. Follow-up at 6 months after the procedure was available in 18 patients and 19 aneurysms. Of the 19 aneurysms, 2 of 12 initially completely occluded aneurysms (17%) and 1 of 7 aneurysms with initial residual necks (14%) showed recanalization at the 6-month follow-up. One recanalized aneurysm was subsequently recoiled with consequent residual neck and remained unchanged at the 1-year follow-up. Embolization by TruFill platinum coils has a comparable total aneurysmal occlusion rate to that with GDC. The mid-term reintervention rate is low, and will require verification by future long-term studies.

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