Send to

Choose Destination
Br J Dermatol. 2006 Apr;154(4):759-62.

Acquired reactive perforating collagenosis: four patients with a giant variant treated with allopurinol.

Author information

Department of Dermatology, St Helier Hospital, Carshalton SM5 1AA, UK.


Reactive perforating collagenosis (RPC) is one of the four essential acquired perforating dermatoses. The condition is characterized by the transepidermal elimination of altered collagen. This paper describes four patients with a giant variant of RPC which has not previously been documented. Three of the patients had associated diabetes mellitus and one had chronic renal failure secondary to fetal scarring. Three of the four patients had a significant improvement in their lesions and symptoms following treatment with allopurinol.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center