Format

Send to

Choose Destination
See comment in PubMed Commons below
Clin Perinatol. 2006 Mar;33(1):169-82, ix.

Modest hypothermia as a neuroprotective strategy in high-risk term infants.

Author information

1
Department of Neonatology, Texas Children's Hospital, Houston, TX 77030, USA.

Abstract

This article briefly reviews the pathogenesis of hypoxic-ischemic cerebral injury, the experimental data, and clinical studies that have evaluated the potential therapeutic benefit of modest selective or whole body hypothermia in reducing the subsequent development of irreversible brain injury without untoward side effects. Data are insufficient to recommend routine use of either modest selective or whole body hypothermia after resuscitation of infants with suspected asphyxia. Further clinical trials are needed to determine which infants would benefit most and which method of cooling would be most effective.

PMID:
16533643
DOI:
10.1016/j.clp.2005.11.012
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center