Histamine, mast cells, and the enteric nervous system in the irritable bowel syndrome, enteritis, and food allergies

J D Wood

doi:10.1136/gut.2005.079046

Histamine, mast cells, and the enteric nervous system in the irritable bowel syndrome, enteritis, and food allergies

Gut. 2006 Apr;55(4):445-7. doi: 10.1136/gut.2005.079046.

Author

J D Wood¹

Affiliation

¹ Department of Physiology and Cell Biology, The Ohio State University College of Medicine, 304 Hamilton Hall, 1645 Neil Ave, Columbus, Ohio 43210-1218, USA. wood.13@osu.edu

Abstract

There is altered expression of histamine H₁ and H₂ receptor subtypes in mucosal biopsies from the terminal ileum and large intestine of patients with symptoms of food allergy and/or irritable bowel syndrome

Publication types

Comment

MeSH terms

Enteritis / immunology
Enteritis / metabolism*
Food Hypersensitivity / immunology
Food Hypersensitivity / metabolism*
Histamine / immunology
Humans
Ileum / immunology
Intestinal Mucosa / immunology
Intestine, Large / immunology
Intestine, Small / immunology
Intestine, Small / innervation
Irritable Bowel Syndrome / immunology
Irritable Bowel Syndrome / metabolism*
Mast Cells / immunology
Receptors, Histamine / analysis
Receptors, Histamine / metabolism*
Receptors, Histamine H1 / analysis
Receptors, Histamine H2 / analysis

Substances

Receptors, Histamine
Receptors, Histamine H1
Receptors, Histamine H2
Histamine