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Cell. 2006 Mar 10;124(5):877-81.

Micro RNAs in animal development.

Author information

  • 1Hubrecht Laboratory (KNAW), Utrecht University, 3584CT Utrecht, the Netherlands. plasterk@niob.knaw.nl

Abstract

Micro RNAs (miRNAs) are approximately 22 nucleotide single-stranded noncoding RNA molecules that bind to target messenger RNAs (mRNAs) and silence their expression. This Essay explores the importance of miRNAs in animal development and their possible roles in disease and evolution.

PMID:
16530032
DOI:
10.1016/j.cell.2006.02.030
[PubMed - indexed for MEDLINE]
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