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Clin Pediatr (Phila). 2006 Mar;45(2):123-33.

Effectiveness of an intervention for colic.

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  • 1College of Nursing, University of Utah, 10 South 2000 East, Rm. 410, Salt Lake City, UT 84112, USA.


An intervention for infant irritability or colic was evaluated in a randomized clinical trial. A total of 121 full-term irritable infants (2 to 6 weeks old) were randomized to routine care or the home-based intervention program. A third group (n=43) of irritable infants were entered into a post-test-only group. Following the 4-week intervention, the treatment group infants cried 1.7 hours less per day than the infants in the control group (p=0.02). The findings support the emerging view of infant colic as a behavioral pattern that is responsive to environmental modification and structured cue-based care.

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