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J Wildl Dis. 1970 Oct;6(4):443-7.

Mechanism of spring relapse in avian malaria: effect of gonadotropin and corticosterone.

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  • 1Naval Medical Research Institute, Bethesda, Maryland 20014, USA.

Abstract

Previous work demonstrated that corticosterone induces relapse of avian malaria, and that this effect varies markedly from winter to spring. In the present study, English sparrows with latent Plasmodium relictum infections were treated in winter with corticosterone, gonadotropin, corticosterone + gonadotropin, or a control regimen consisting of the oil vehicle. Gonadotropin neither induced relapse nor potentiated the induction of relapse by corticosterone. These data cast doubt on the hypothesis that spring relapse in malarial infections is mediated by seasonal changes in reproductive hormone levels.

PMID:
16512154
[PubMed - indexed for MEDLINE]
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