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Infection. 2006 Feb;34(1):22-5.

Distribution of four capsular serotypes of Enterococcus faecalis among clinical isolates from different geographical origins and infection sites.

Author information

1
Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Abstract

BACKGROUND:

Enterococci possess capsular polysaccharide antigens that are the targets of opsonic antibodies. These antibodies are potential candidates for development as immunotherapy.

MATERIAL AND METHODS:

The present study analyzes the distribution of four capsular serotypes within a collection of 157 isolates of Enterococcus faecalis from four countries with different sites of clinical infection.

RESULTS:

By using a capsular polysaccharide-specific ELISA, 42% of the isolates were grouped into one of four serogroups, and another 9% showed cross-reactivity between two serotype-specific sera. Heterogeneity of serotype distribution by both geographical origin and infection site was observed.

CONCLUSION:

Half of the strain collection could be typed with four serotype-specific sera. No serotype from a given country or infection site clearly predominated.

PMID:
16501898
DOI:
10.1007/s15010-006-4100-5
[Indexed for MEDLINE]

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