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Emerg Med J. 2006 Mar;23(3):221-3.

Best evidence topic report. Intranasal naloxone in suspected opioid overdose.

Author information

1
Blackburn Royal Infirmary.

Abstract

A short cut review was carried out to establish whether intransasal naloxone is effective in suspected opiate overdose. 596 papers were screened, of which eight presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are tabulated. The clinical bottom line is that it is likely that intranasal Naloxone is a safe and effective first line prehospital intervention in reversing the effects of an Opioid overdose and helping to reduce the risk of needle stick injury. A large, well conducted trial into it's usage is however required to confirm this.

PMID:
16498165
PMCID:
PMC2464442
DOI:
10.1136/emj.2005.034322
[Indexed for MEDLINE]
Free PMC Article

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