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Cell. 2006 Feb 24;124(4):715-27.

Bacterial adhesion and entry into host cells.

Author information

1
Institut Pasteur, Unité des Interactions Bactéries-Cellules, Paris, F-75015 France. pizarroj@pasteur.fr

Abstract

Successful establishment of infection by bacterial pathogens requires adhesion to host cells, colonization of tissues, and in certain cases, cellular invasion-followed by intracellular multiplication, dissemination to other tissues, or persistence. Bacteria use monomeric adhesins/invasins or highly sophisticated macromolecular machines such as type III secretion systems and retractile type IV pili to establish a complex host/pathogen molecular crosstalk that leads to subversion of cellular functions and establishment of disease.

PMID:
16497583
DOI:
10.1016/j.cell.2006.02.012
[Indexed for MEDLINE]
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