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Cell. 2006 Feb 24;124(4):677-81.

The rational design of an AIDS vaccine.

Author information

1
Vaccine Research Center, NIAID, National Institutes of Health, Room 4502, Building 40, MSC-3005, 40 Convent Drive, Bethesda, MD 20892, USA.

Abstract

The extraordinary genetic diversity and immune evasion of human immunodeficiency virus (HIV) pose significant challenges for vaccine development. AIDS vaccine design requires a scientifically driven, rational approach that encompasses the latest advances in viral molecular genetics, structural biology, and immunology.

PMID:
16497577
DOI:
10.1016/j.cell.2006.02.005
[Indexed for MEDLINE]
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