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Dermatology. 2006;212(2):108-12.

Risk factors for erysipelas of the leg in Tunisia: a multicenter case-control study.

Author information

1
Department of Dermatology, La Rabta Hospital, Tunis, Tunisia.

Abstract

BACKGROUND:

Risk factors for erysipelas (cellulitis) were rarely evaluated in controlled studies. Regional variations of these risk factors have never be assessed.

OBJECTIVE:

To assess risk factors for erysipelas of the leg in Tunisia.

SUBJECTS AND METHODS:

Case-control study in seven hospital centers in Tunisia. Cases were 114 consecutive patients with erysipelas of the leg [sudden onset (<24 h) of a well-demarcated dermo-hypodermatitis with fever or chills]. Two controls were matched to each case for age, sex, and hospital (n = 208). Main outcome measures are local and general suspected risk factors for erysipelas of the leg.

RESULTS:

In multivariate analysis, disruption of the cutaneous barrier (i.e. traumatic wound, toe-web intertrigo, excoriated leg dermatosis or plantar squamous lesions) and leg edema were independently associated with erysipelas of the leg, with respective odds ratios of 13.6 (95% confidence interval: 6.0-31) and 7.0 (1.3-38). No association was observed with diabetes, alcoholism, or smoking.

CONCLUSIONS:

We confirmed the major role of local risk factors and the minor role of general risk factors for erysipelas of the leg, in a setting different than the one previously studied. Detecting and treating toe-web intertrigo and traumatic wounds should be considered in the prevention of erysipelas of the leg.

PMID:
16484815
DOI:
10.1159/000090649
[Indexed for MEDLINE]

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