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Items: 3

1.

Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor.

Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2788-93. Epub 2006 Feb 13.

2.

Hot-spot mimicry of a cytokine receptor by a small molecule.

Thanos CD, DeLano WL, Wells JA.

Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15422-7. Epub 2006 Oct 10.

3.

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'.

Levin AM, Bates DL, Ring AM, Krieg C, Lin JT, Su L, Moraga I, Raeber ME, Bowman GR, Novick P, Pande VS, Fathman CG, Boyman O, Garcia KC.

Nature. 2012 Mar 25;484(7395):529-33. doi: 10.1038/nature10975.

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