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J Infect Dis. 1991 Jul;164(1):170-1.

Evaluation of the effect of drugs on the cyst form of Toxoplasma gondii.

Author information

1
Department of Immunology and Infectious Diseases, Palo Alto Medical Foundation, CA 94301.

Abstract

The cyst form of Toxoplasma gondii has been implicated as a cause of recrudescence of the latent infection in congenitally infected patients and in the immunocompromised host. A method was developed to evaluate the effect of drugs on the cyst form of the parasite and used to evaluate a variety of therapeutic agents. The most active compounds against the cyst form in vitro were arprinocid-N-oxide, azithromycin, and the hydroxynaphthoquinone 566C80.

PMID:
1647421
DOI:
10.1093/infdis/164.1.170
[Indexed for MEDLINE]

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