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Cell Microbiol. 2006 Mar;8(3):375-86.

Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells.

Author information

1
Institute of Molecular Virology (IMV) Westfaelische-Wilhelms-University, Von-Esmarch Str. 56, D-48161 Muenster, Germany. ludwigs@uni-muenster.de

Abstract

Small RNA viruses such as influenza viruses extensively manipulate host-cell functions to support their replication. At the same time the infected cell induces an array of defence mechanisms to fight the invader. These processes are mediated by a variety of intracellular signalling cascades. Here we will review the current knowledge of functional kinase signalling and apoptotic events in influenza virus infected cells and how these viruses have learned to misuse these cellular responses for efficient replication.

[Indexed for MEDLINE]

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