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Int J STD AIDS. 2006 Feb;17(2):81-92.

UK Guideline for the use of post-exposure prophylaxis for HIV following sexual exposure.

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  • 1Department of Genitourinary Medicine, Royal Sussex County Hospital, Brighton, UK.


We present the British Association for Sexual Health and HIV (BASHH) guidelines for post-exposure prophylaxis after sexual exposure (PEPSE) to HIV. This document includes a review of the current data to support the use of PEPSE, considers how to calculate the risks of HIV infection after a potential exposure, and provides recommendations on when PEPSE would and would not be considered. Other areas included are the possible impact on sexual behaviour, cost-effectiveness, and issues relating to service provision. Throughout the document, consideration is given to the place of PEPSE within the broader context of HIV prevention strategies and sexual health.

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