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J Clin Ultrasound. 1991 May;19(4):221-3.

Fetal loss rate after ultrasonically documented cardiac activity between 6 and 14 weeks, menstrual age.

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Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh, School of Medicine, Pennsylvania 15213.


The pregnancy outcome of 347 patients with a confirmed, viable intrauterine pregnancy between 6.0 and 14.0 weeks, menstrual age, was determined. The miscarriage rate was 4.2% in a subgroup of patients without vaginal bleeding, as compared with 12.7% in a subgroup with bleeding (chi 2 = 7.4, p less than 0.006). First trimester vaginal bleeding was a significant covariate in the determination of the spontaneous miscarriage rate after fetal cardiac activity has been confirmed.

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