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Parkinsonism Relat Disord. 2006 May;12(4):257-60. Epub 2006 Feb 3.

Reversible Parkinsonian syndrome associated with anti-neuronal antibodies in acute EBV encephalitis: a case report.

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  • 1Department of Neurologic and Psychiatric Sciences-University of Bari, Giulio Cesare, 2 70124 Bari (BA), Italy.


We report a case of subacute-onset isolated parkinsonian syndrome in a 16 years old patient. Epstein-Barr infection was diagnosed according to serologic evidences. Parkinson-like syndrome completely recovered after 60 days. Autoantibodies reacting against a 130 Kda antigens expressed in human neuroblastoma cell line were detected. Pathogenesis and differential diagnosis are briefly discussed. EBV testing could be worthwhile in juvenile, acute-onset, parkinsonism.

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