Abstract
An overview is presented of selected metal-based pharmaceuticals, either diagnostic or therapeutic, with emphasis on specific attributes and in vivo interactions of these compounds relevant to their use in medicinal applications. Both the advantages and the challenges of this approach are outlined, with possibilities for future developments accentuated.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chemistry, Pharmaceutical / methods*
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Computer-Aided Design
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Drug Design*
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Drug Evaluation, Preclinical
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Inorganic Chemicals
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Ligands
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Models, Molecular
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Molecular Conformation
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Molecular Structure
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Pharmaceutical Preparations / chemistry*
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Structure-Activity Relationship
Substances
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Inorganic Chemicals
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Ligands
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Pharmaceutical Preparations