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Res Microbiol. 2006 May;157(4):299-305. Epub 2005 Dec 29.

TrwB: an F(1)-ATPase-like molecular motor involved in DNA transport during bacterial conjugation.

Author information

1
Departamento de BiologĂ­a Molecular (Unidad Asociada al CIB-CSIC), Universidad de Cantabria, C. Herrera Oria s/n, 39011 Santander, Spain.

Abstract

The mechanism by which TrwB acts as a DNA transporter in bacterial conjugation is analyzed. Based on a parallelism between TrwB and F(1)-ATPase, TrwB would use the energy derived from ATP hydrolysis to pump DNA through its central channel, in a manner similar to that used by F(1)-ATPase to produce a rotary movement of the central gamma-subunit.

PMID:
16427770
DOI:
10.1016/j.resmic.2005.12.002
[Indexed for MEDLINE]

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