Format

Send to

Choose Destination
See comment in PubMed Commons below
Brain Cogn. 2006 Apr;60(3):220-32. Epub 2006 Jan 19.

Study design in fMRI: basic principles.

Author information

1
Neuroimaging Research Group, Institute of Psychiatry, King's College, University College, London, UK. eamaro@usp.br

Abstract

There is a wide range of functional magnetic resonance imaging (fMRI) study designs available for the neuroscientist who wants to investigate cognition. In this manuscript we review some aspects of fMRI study design, including cognitive comparison strategies (factorial, parametric designs), and stimulus presentation possibilities (block, event-related, rapid event-related, mixed, and self-driven experiment designs) along with technical aspects, such as limitations of signal to noise ratio, spatial, and temporal resolution. We also discuss methods to deal with cases where scanning parameters become the limiting factor (parallel acquisitions, variable jittered designs, scanner acoustic noise strategies).

PMID:
16427175
DOI:
10.1016/j.bandc.2005.11.009
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center