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Immunology. 2006 Feb;117(2):145-55.

CD45: all is not yet crystal clear.

Author information

1
Division of Immunology, Department of Pathology, Cambridge University, UK. nh106@cam.ac.uk

Abstract

CD45 has been recognized as an important player in regulating signalling in lymphocytes. However, compared with tyrosine kinases, phosphatases are still poorly understood in terms of the details of their specificity and regulation. Here, the recent progress in understanding the biology of the first recognized receptor tyrosine phosphatase, CD45, is reviewed.

PMID:
16423050
PMCID:
PMC1782222
DOI:
10.1111/j.1365-2567.2005.02265.x
[Indexed for MEDLINE]
Free PMC Article
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