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Andrologia. 2006 Feb;38(1):34-7.

Dramatic improvement of penile venous leakage upon testosterone administration. A case report and review of literature.

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Clinic of Urology/Andrology, Segeberger Kliniken, Norderstedt-Hamburg, Germany.


The main effect of testosterone was long-time assumed to be on sexual interest and, indirectly, on erectile function. Newer insights demonstrate that testosterone deficiency impairs the anatomical, ultrastructural, biological and physiological/functional substrate of penile erection, which can be, at least in part, restored by normalization of plasma testosterone levels. This is a report on a 56-year-old man suffering from diabetes mellitus type II and metabolic syndrome, who had complaints of a severe erectile dysfunction because of venous leakage, confirmed by pharmaco-cavernosography. He was also testosterone deficient (1.8 ng ml(-1)). Upon testosterone administration his erectile function improved dramatically. Repeated cavernosography no longer showed venous leakage.

[Indexed for MEDLINE]

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