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Methods Enzymol. 2005;405:1-36.

Molecular weight determination of peptides and proteins by ESI and MALDI.

Author information

1
Thermo Electron GmbH (Bremen), Germany.

Abstract

Several topics are covered, namely, general aspects important for mass determination of peptides and proteins, sample preparation for both ESI and MALDI, and various mass analyzers coupled to these ionization techniques. Finally, the discussion is carried out on peptide and protein mass analysis as related to accuracy and precision of mass determination for both ESI-MS and MALDI-MS.

PMID:
16413308
DOI:
10.1016/S0076-6879(05)05001-9
[Indexed for MEDLINE]

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