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Md Med J. 1992 Jul;41(7):609-13.

Aging and humoral immunity.

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Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore 21201.


If human antibody responses undergo molecular shifts similar to those identified in mice, the appropriate immunization strategy for the elderly would be a passive administration of the protective antibody from young donors rather than an attempt to boost the individual's own response with a more potent vaccine, because the shifted immune system can no longer make the right kind of antibody.

[Indexed for MEDLINE]

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