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Biol Pharm Bull. 2006 Jan;29(1):172-3.

Inhibition of Helicobacter pylori motility by (+)-Syringaresinol from unripe Japanese apricot.

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1
Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University. miyazawa@apch.kindai.ac.jp

Abstract

A methanol extract from unripe Japanese apricot showed inhibitory activity of Helicobacter pylori motility. Inhibitory compound 1 was isolated and identified as (+)-syringaresinol (1) by spectoroscopic means. (+)-Syringaresinol (1) inhibited >90% of the H. pylori motility at a concentration of 500 microg/ml and the IC50 value was 50 microg/ml.

PMID:
16394533
[Indexed for MEDLINE]
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