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Cleve Clin J Med. 2005 Dec;72(12):1105-12.

Frailty in older adults: insights and interventions.

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  • 1Department of Geriatric Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.


Frailty is a state of vulnerability that carries an increased risk of poor outcomes in older adults. Common signs and symptoms are fatigue, weight loss, muscle weakness, and progressive decline in function. Frail older adults are among the most challenging for medical management. However, awareness of this syndrome and its risks can help us care for these patients more confidently and decrease their risk for adverse outcomes.

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