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Eur J Anaesthesiol. 2006 Jan;23(1):17-22.

Long-term outcome of patients who require renal replacement therapy after cardiac surgery.

Author information

1
Università Vita-Salute di Milano, IRCCS San Raffaele Hospital, Department of Cardiovascular Anaesthesia and Intensive Care, Italy. landoni.giovanni@hsr.it

Abstract

BACKGROUND AND OBJECTIVE:

Acute renal failure is a serious complication of cardiac surgery. We studied the long-term survival and quality of life of patients requiring renal replacement therapy after cardiac surgery, since they represent a heavy burden on hospital resources and their outcome has never been adequately evaluated.

METHODS:

Out of 7846 consecutive cardiac surgical patients, 126 (1.6%) required postoperative renal replacement therapy: their preoperative status and hospital course was compared with patients who had no need of postoperative renal replacement therapy. A multivariate analysis identified predictors of renal replacement therapy. Long-term survival and quality of life was collected in patients who had renal replacement therapy and in case-matched controls.

RESULTS:

Hospital mortality in the study group was 84/126 (66.7%) vs. 118/7720 (1.5%) in the control population (P 1000 mL, chronic obstructive pulmonary disease and age.

CONCLUSIONS:

This study confirms that the in-hospital mortality of patients requiring renal replacement therapy is high and shows a low long-term mortality with reasonable quality of life in patients discharged from hospital alive.

PMID:
16390560
DOI:
10.1017/S0265021505001705
[Indexed for MEDLINE]

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