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Br J Psychiatry. 2006 Jan;188:32-6.

Obstetric variables associated with bipolar affective puerperal psychosis.

Author information

1
Neuropsychiatric Genetics Unit, Department of Psychological Medicine, University of Cardiff, Heath Park, Cardiff CF14 4XN, Wales, UK.

Abstract

BACKGROUND:

Previous cross-sectional studies have highlighted a number of obstetric variables that may be associated with the development of broadly defined puerperal (post-partum) psychosis. These include: (a) primiparity, (b) pregnancy complications, (c) delivery complications, (d) Caesarean section, (e) female baby and (f) shorter gestation period.

AIMS:

To examine these risk factors in women with well-characterised bipolar affective puerperal psychosis.

METHOD:

A sample of 129 women with bipolar affective puerperal psychosis were investigated using a design that takes advantage of within-subject comparisons of affected and unaffected deliveries.

RESULTS:

Two of the variables studied were independently associated with an episode of puerperal psychosis: primiparity (odds ratio=3.76, P < 0.001) and delivery complications (odds ratio=2.68, P=0.022).

CONCLUSIONS:

This study provides further evidence of the association between primiparity and puerperal psychosis and suggests that complications during delivery may be associated with a severe post-partum episode.

PMID:
16388067
DOI:
10.1192/bjp.188.1.32
[Indexed for MEDLINE]

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