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Clin Lung Cancer. 2005 Dec;7 Suppl 3:S93-7.

Therapeutic strategies for combined-modality therapy of locally advanced non-small-cell lung cancer: rationale for consolidation docetaxel therapy.

Author information

  • 1Department of Hematology/Oncology, University of California Davis Cancer Center, Sacramento, CA 95817-2229, USA. david.gandara@ucdmc.ucdavis.edu

Abstract

Currently, there is no accepted standard of care for locally advanced and surgically unresectable non-small-cell lung cancer. Typically, treatment for patients with good performance status consists of a combination of chemotherapy and thoracic radiation therapy (RT), but the integration of these modalities and the respective dose schedules vary considerably. Herein, we review the rationale for a treatment paradigm employing consolidation docetaxel therapy after concurrent chemotherapy/RT and the results of recent clinical trials using this approach.

PMID:
16384543
[PubMed - indexed for MEDLINE]
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