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Br J Obstet Gynaecol. 1992 Jun;99(6):512-5.

Cord insulin and C-peptide--distribution in an unselected population.

Author information

1
University Department of Obstetrics and Gynaecology, Northern General Hospital, Sheffield, UK.

Abstract

OBJECTIVE:

To assess the distribution of cord blood insulin in an unselected population, and examine its relation to birthweight centiles.

SETTING:

District General Hospital in Nottinghamshire.

SUBJECTS:

209 unselected singleton births.

MEAN OUTCOME MEASURE:

Cord blood insulin; cord blood C-peptide; birthweight centiles.

RESULTS:

Hyperinsulinaemic babies (greater than 97th centile for cord insulin) were found at all birthweight centiles. 15% of high birthweight babies were hyperinsulinaemic. For low birthweight babies, the distribution of cord insulin/C-peptide was skewed indicating a high number of low values. Hypoinsulinaemic babies were present up to the 50th centile for birthweight.

CONCLUSIONS:

Abnormalities of fetal insulinisation may be found in babies of all birthweights.

[Indexed for MEDLINE]

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