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Cell Biol Int. 2006 Mar;30(3):205-9. Epub 2005 Dec 22.

Does yeast shmooing mean a commitment to apoptosis?

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1
Department of Biochemistry and Cell Biology, University of Rzeszów, ul. Rejtana 16C, 35-959 Rzeszów, Poland.

Abstract

Treatment of yeast Saccharomyces cerevisiae with alpha-pheromone has been reported to lead to massive apoptosis of cells finding no conjugation partner [Severin FF, Hyman AA. Pheromone induces programmed cell death in S. cerevisiae. Curr Biol 2002;12:R233-5]. We report here that this effect is not common in yeast. Using different yeast strains, we demonstrate that identical treatment results in a low mortality even after prolonged treatment with the pheromone. These findings are followed by a general discussion of the biological relevance of apoptosis in yeast.

PMID:
16376583
DOI:
10.1016/j.cellbi.2005.10.023
[Indexed for MEDLINE]
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