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Curr Opin Chem Biol. 2006 Feb;10(1):4-10. Epub 2005 Dec 22.

Recent advances of protein microarrays.

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1
Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, D-14195 Berlin, Germany.

Abstract

Technological innovations and novel applications have greatly advanced the field of protein microarrays. Over the past two years, different types of protein microarrays have been used for serum profiling, protein abundance determinations, and identification of proteins that bind DNA or small compounds. However, considerable development is still required to ensure common quality standards and to establish large content repertoires. Here, we summarize applications available to date and discuss recent technological achievements and efforts on standardization.

PMID:
16376134
DOI:
10.1016/j.cbpa.2005.12.011
[Indexed for MEDLINE]
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