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Cornea. 2006 Feb;25(2):199-202.

Adenoviral keratoconjunctivitis in a tertiary care eye clinic.

Author information

1
Molecular Pathogenesis of Eye Infection Research Center, Dean A. McGee Eye Institute, Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.

Abstract

PURPOSE:

To elucidate the natural history and epidemiology of adenoviral keratoconjunctivitis as seen in a tertiary care eye clinic.

METHODS:

In a retrospective observational case series design, the medical records of 54 consecutive patients seen over a 6-year period at the Dean McGee Eye Institute (DMEI) with a diagnosis of adenoviral keratoconjunctivitis were analyzed retrospectively. The main outcome measure was the duration of symptomatic subepithelial corneal infiltrates following onset of acute conjunctivitis.

RESULTS:

Annual case numbers ranged from 3 each in 1997 and 1998 to 26 in 2000. No more than 5 new cases presented in any single month, and no seasonal predominance was evident. The median duration of disease was 5 weeks, but the mean was 23.4 weeks, reflecting a subset of patients with a prolonged course. Indeed, 14 (25.9%) of 54 patients demonstrated symptomatic subepithelial corneal infiltrates for more than 45 days from the first examination for conjunctivitis.

CONCLUSION:

These data suggest a significant level of long-term morbidity for adenoviral keratoconjunctivitis.

PMID:
16371782
[Indexed for MEDLINE]

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