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J Exp Med. 2005 Dec 19;202(12):1623-6.

Functionally distinct NKT cell subsets and subtypes.

Author information

1
RIKEN Research Center for Allergy and Immunology, Yokohama City, Kanagawa 230-0045, Japan.

Abstract

Natural killer T (NKT) cells are a population of autoreactive cells that mediate both protective and regulatory immune functions. NKT cells comprise several subsets of cells, but it has been unclear whether these different NKT cell subsets possess distinct functions in vivo. New studies now demonstrate that subsets of NKT cells are indeed functionally distinct and that the specific functions of these cells may be dictated in part by organ-specific mechanisms.

PMID:
16365145
PMCID:
PMC2212962
DOI:
10.1084/jem.20051600
[Indexed for MEDLINE]
Free PMC Article
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