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Parkinsonism Relat Disord. 2006 Mar;12(2):65-71. Epub 2005 Dec 20.

Movement disorders and Creutzfeldt-Jakob disease: a review.

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Department of Neurology, Rouen University Hospital, Charles Nicolle, 1 Germont Street 76031 Rouen Cedex, France.


Movement disorders are reported in a significant number of patients within the course of Creutzfeldt-Jakob disease (CJD). Although myoclonus is more frequent, dystonia, choreoathetosis, tremor, hemiballismus, and atypical parkinsonian syndromes have also been reported. In this review, we report the principal movement disorders associated with CJD and evaluate their correlations with neuroradiological and neuropathological findings that could in fact suggest a basal ganglia dysfunction. Further studies are warranted in order to clarify these correlations.

[Indexed for MEDLINE]

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