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Toxicon. 2006 Feb;47(2):156-62. Epub 2005 Dec 13.

First report on cylindrospermopsin producing Aphanizomenon flos-aquae (Cyanobacteria) isolated from two German lakes.

Author information

1
Federal Environmental Agency, FG II 3.3, Corrensplatz 1, 14195 Berlin, Germany. karina.preussel@uba.de

Abstract

Three single-filament isolates of Aphanizomenon flos-aquae from two German lakes were found to produce remarkable amounts of the cyanobacterial hepatotoxin cylindrospermopsin (CYN). CYN-synthesis of the strains were evidenced both by LC-MS/MS analysis and detection of PCR products of gene fragments which are implicated in the biosynthesis of the toxin. The strains contain CYN in the range of 2.3-6.6 mg g(-1) of cellular dry weight. To our knowledge this is the first report of CYN in A. flos-aquae.

PMID:
16356522
DOI:
10.1016/j.toxicon.2005.10.013
[Indexed for MEDLINE]

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