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Nature. 2005 Dec 15;438(7070):932-6.

Angiogenesis in life, disease and medicine.

Author information

1
Center of Transgene Technology and Gene Therapy, University of Leuven, Flanders Interuniversity Institute for Biotechnology (VIB), B-3000 Leuven, Belgium. peter.carmeliet@med.kuleuven.be

Abstract

The growth of blood vessels (a process known as angiogenesis) is essential for organ growth and repair. An imbalance in this process contributes to numerous malignant, inflammatory, ischaemic, infectious and immune disorders. Recently, the first anti-angiogenic agents have been approved for the treatment of cancer and blindness. Angiogenesis research will probably change the face of medicine in the next decades, with more than 500 million people worldwide predicted to benefit from pro- or anti-angiogenesis treatments.

PMID:
16355210
DOI:
10.1038/nature04478
[Indexed for MEDLINE]

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